Advances in calorimetry for drug discovery

SBS Symposium Keynote Address

2 November 2009

Bio-sensor arrays on flexible polyimide substrates for drug discovery applications

MRS Spring Meeting 2006

19 April 2006

Crystal structure and thermodynamic characterization of the EphB4 receptor in complex with an ephrin-B2 antagonist peptide reveals the determinants for receptor specificity

Structure

1 February 2006

Detecting the fluorescence emission wavelength using a spatially modulated color mask in a compact flow cytometer platform

CYTO 2011

20 May 2011

Enthalpy array analysis of enzymatic and binding reactions

Analytical Biochemistry

June 2008

Enthalpy arrays

Proceedings of the National Academy of Sciences

29 June 2004

Enzymatic assays for fragment-based screening using enthalpy arrays

Drug Discovery Chemistry: Fragment-based Techniques

6 April 2009

Flow cytometry on a chip

To be published in “Point of Care Diagnostics on a Chip”

2013

Fragment-based screening for inhibitors of PDE4A using enthalpy arrays and X-ray crystallography

Journal of Biomolecular Screening

January 2012

Handheld flow cytometer for rapid pathogen characterization in water

2012 Materials Research Society Fall Meeting

25 November 2012

Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays

Analytical Biochemistry

15 May 2009

MEMS-based enthalpy arrays

Transducers '07

10 June 2007

Micro-fluidic based detection platform for rapid pathogen characterization in water

Frontiers in Optics 2012 and Laser Science XXVIII

14 October 2012

Modeling the PARC nanocalorimeter using COMSOL

COMSOL Users Conference

26 October 2006

Monitoring assembly of ribonucleoprotein complexes by isothermal titration calorimetry

Methods in Molecular Biology

2008

On-the-flow pathogen detection in water

SPIE Defense, Security and Sensing Symposium 2011

25 April 2011

Opto-fluidic detection system enabling sophisticated point-of-care diagnostics

First Annual SLAS (Society for Laboratory Automation and Screening) Conference and Exhibition

4 February 2012

Opto-fluidic detection system enabling sophisticated point-of-care diagnostics

Invited Seminar, Stanford Optical Society, Stanford University

5 April 2012

Quantitative analysis of protein-RNA interactions by gel mobility shift

Methods in Molecular Biology

2008

Rapid mixing of sub-microliter drops by magnetic micro-stirring

Lab on a Chip

October 2011

Structural and biophysical characterization of the EphB4-ephrinB2 protein interaction and receptor specificity

Journal of Biological Chemistry

25 July 2006

Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition

Journal of Biological Chemistry

December 2007

Time encoded multicolor fluorescence detection in a microfluidic flow cytometer

Lab on a Chip

2012