home › event - advances in calorimetry for drug discovery

EVENT:

Advances in calorimetry for drug discovery
Conferences & Talks

SBS Symposium: Advances & Challenges in Label-Free Technologies for Drug Discovery

2 November 2009 - 3 November 2009
San Diego, California, USA

 

description

Calorimetry is a universally applicable label-free and immobilization-free method that directly measures heat changes associated with binding interactions, enzymatic reactions, cell growth, and macromolecule folding and stability. Isothermal titration calorimetry (ITC), the only method that can simultaneously determine all binding parameters (enthalpy, entropy, affinity, and number of sites) in a single experiment, has long been regarded as the gold standard assay for binding. Due to the low throughput and relatively large quantities of material required for the measurements, the application of ITC in drug discovery has been limited.

This presentation looks at the advances in the miniaturization of calorimeters and how the increased throughput and reduced sample consumption of these devices could expand the application of calorimetry in drug discovery.

 

upcoming events   view all 

Aston Martin: The Brand Journey of a 100 Year-old Startup
Mr. Simon Sproule
29 August 2016
PARC Forum  

A Low-cost and Innovative Radar “Digital Eye”
Bernard Casse
20 September 2016 - 22 September 2016 | Brussels, Belgium
Conferences & Talks  

Stanford and PARC host Digital Cities Summit 2016
Victoria Bellotti, Panel Facilitator, Bernard Casse, Panelist, Sean Garner, Panelist, Stephen Hoover, Keynote Speaker, Matthew Klenk, Tolga Kurtoglu, Panel Facilitator, Markus Larsson, Speaker, Ersin Uzun, Panelist
3 October 2016 - 4 October 2016 | Stanford, CA
Conferences & Talks