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Traveling wave bio-agent concentrator


This paper describes a hybrid bio-agent concentrator device based on the combined performance of a modified field flow fractionation device for particulate deposition and a traveling wave transport mechanism to deliver and concentrate particulates into a sample well. The operating principles are based on MEMS technology for precise particulate control and manipulation. This device may increase the concentration of post-ultrafiltration retentates or post-aerosol collected hydrosols by another 100X. As a front-end to detection, it will enhance the effective sensitivity of the detector. The device may also have bio medical implications in cell enrichment.


Lean, M. ; Voelkel, A. R. ; Hsieh, H. B. ; Lu, J. P. ; Daniel, J. H. ; Preas, B. T. ; Limb, S. Traveling wave bio-agent concentrator. 3rd IEEE-EMBS Special Topic Conference on Microtechnology in Medicine and Biology; 2005 May 12-15; Honolulu; HI; USA. Piscataway, NJ: IEEE; 2005; 80-83.