Human DNA Variation and Complex Traits

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George E. Pake Auditorium 2006-11-15

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Event

Human DNA Variation and Complex Traits

Dr. Frazer joined Perlegen Sciences in January 2000, with a strong background in the field of genomics. While at Perlegen, Dr. Frazer has directed HapMap Phase II project, an international effort to genotype a large fraction of common SNPs in the genome. Dr. Frazer is currently leading a genome-wide SNP delivery project in the mouse genome and in collaboration with scientists at the Whitehead Institute in characterizing the segmental structure of variation in inbred mouse strains. Recently, Dr. Frazer's research has shown that common structural polymorphisms in humans are in linkage disequilibrium with common SNPs. Her research interests also include understanding the molecular mechanisms underlying allele-specific expression differences as well as the physiological relevance of such expression differences.

Dr. Kelly Frazer received her Ph.D. degree from the Biomedical Sciences program at the University of California, San Francisco and then held a Research Scientist position in the Genome Science Department of Lawrence Berkeley National Laboratory. She has been a Program Committee member for several nationally organized scientific meetings, including the annual Cold Spring Harbor Laboratory Genomicsw Conference and the 2006 Human Genome Meeting. She has co-authored over 30 peer-reviewed scientific publications.

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