On-the-flow absorption and refractive index measurements in a microfluidic device

Details

Event

2009-01-24
Event

On-the-flow absorption and refractive index measurements in a microfluidic device

In conventional absorption spectroscopy the detection of small absorption changes requires a long interaction length, typically on the order of the absorption length, and therefore large sample volumes. In a lab-on-a-chip approach, the interaction length must be prolonged inside the device. We enhance the sensitivity with a Fabry-Pérot etalon inside a microfluidic channel. While the changes of the refractive index result in a shift of the Fabry-Pérot peak position, absorption within the optical cavity is causing a change of the amplitude and the width of the modes. The method is insensitive to intensity variations outside the fluidic channel since the transmitted light also provides the referencing signal.

Additional information

Focus Areas

Our work is centered around a series of Focus Areas that we believe are the future of science and technology.

FIND OUT MORE
Licensing & Commercialization Opportunities

We’re continually developing new technologies, many of which are available for Commercialization.

FIND OUT MORE
News

PARC scientists and staffers are active members and contributors to the science and technology communities.

FIND OUT MORE