Sub-mK optical thermometry in picoliter droplets

Details

Khaosiung, USA. Date of Talk: 2018-11-14

Speakers

Jacob Chamoun
Pattekar, Ashish V.
Farzaneh Afshinmanesh
Recht, Michael I.
Event

Sub-mK optical thermometry in picoliter droplets

On the flow temperature measurements in 500 pL droplets traversing a microfluidic channel are presented. In this system, thermochromic liquid crystal (TLC) reporter particles suspended in aqueous droplets change their color in response to a temperature change. An optical readout interprets the color change to derive temperature information. The noise in the temperature measurement on a single droplet was 11 mK, and the time-averaged noise was 0.6 mK over the full measurement time of 1 s. These results present a path to a high-throughput calorimeter platform for analysis of biochemical interactions.

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