Reanalysis of tyrannosaurus rex mass spectra

Details

Event Journal of Proteome Research

Authors

Marshall Bern
Goldberg, David
Technical Publications
July 15th 2009
Asara et al. reported the detection of collagen peptides in a 68-million-year-old T. rex bone by shotgun proteomics. This finding has been called into question as a possible statistical artifact. We reanalyze Asara et al.s tandem mass spectra using a different search engine and different statistical tools. Our reanalysis shows a sample containing common laboratory contaminants, soil bacteria, and bird-like hemoglobin and collagen.

Citation

Bern, M. W.; Phinney, B. S.; Goldberg, D. Reanalysis of tyrannosaurus rex mass spectra. Journal of Proteome Research. 2009 September; 8 (9): 4328-4332.

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